engineering.princeton.edu, November 29, 2018
by Adam Hadhazy
@brangwynnelab
New @brangwynnelab manuscript in Biophysical Journal proposes measures to improve condensate analysis by FRAP 👏 👏 👏. What does this mean for the mountains of FRAP data out there? Re-analysis? Re-acquisition?
Quantifying dynamics in phase-separated condensates using fluorescence recovery after photobleaching
Cells contain numerous membrane-less organelles that assemble by intracellular liquid-liquid phase separation. The viscous properties and associated b...
www.cell.com
Cliff to be awarded the Biophysical Society's Bárány award for his "beautiful applications of the principles of soft matter".
https://t.co/adoGcONC1Y
Nicole's Condensate FRAP paper is published! Beautiful data and rigorous analysis resulting from a close collaboration with Nicole's co-advisor Howard Stone (who also served on Cliff's thesis committee at Harvard!). Way to go Nicole!
Quantifying dynamics in phase-separated condensates using fluorescence recovery after photobleaching
Cells contain numerous membrane-less organelles that assemble by intracellular liquid-liquid phase separation. The viscous properties and associated b...
www.cell.com
Steven's paper is out on BioRxiv! Really cool manuscript that has it all - sequence-dependent molecular interaction strengths and phase diagrams, partition coefficients, "bursty" nucleation physics, and transcriptional amplification!
Nucleated transcriptional condensates amplify gene expression
Liquid-liquid phase separation is thought to underly gene transcription, through the condensation of the large-scale nucleolus, or in smaller assembli...
www.biorxiv.org
HIGHLIGHTS
New tools illuminate the liquid forces at play in living cells
Cliff wins MacArthur ‘Genius’ Grant
Cliff selected as HHMI Investigator
Cell Biology’s New Phase
Nature, March 15, 2018
by Elie Dolgin
